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Ingredients8 min readJanuary 9, 2025

Resveratrol & Polyphenols: Nature's Antioxidant Powerhouses

Polyphenols like resveratrol, green tea (EGCG), and ferulic acid provide potent antioxidant protection against photoaging and inflammation.

Dr. Sarah Chen

Dr. Sarah Chen

Board-Certified Dermatologist

Resveratrol & Polyphenols: Nature's Antioxidant Powerhouses

Resveratrol & Polyphenols: Nature's Antioxidant Powerhouses

Polyphenols are plant-derived compounds with 87-90% dermatologist support for their powerful antioxidant, anti-inflammatory, and photoprotective properties.

What Are Polyphenols?

Polyphenols are a diverse group of naturally occurring compounds found in plants. They neutralize free radicals, reduce inflammation, and protect against UV-induced damage.

Key Polyphenols for Skin

Polyphenol Source Primary Benefits
Resveratrol Grapes, berries Anti-aging, photoprotection
EGCG Green tea Antioxidant, anti-inflammatory
Ferulic Acid Rice bran, oats Stabilizes Vitamin C, UV protection
Quercetin Apples, onions Anti-inflammatory, barrier support
Ellagic Acid Pomegranate Brightening, collagen protection

Resveratrol Deep Dive

Resveratrol is the "star" polyphenol, famously found in red wine. In skincare:

Benefits

  • Activates sirtuins - longevity genes that protect cells
  • Neutralizes free radicals - prevents oxidative damage
  • Inhibits melanogenesis - helps with hyperpigmentation
  • Anti-inflammatory - reduces redness and sensitivity
  • Stability Concerns

    Resveratrol is notoriously unstable. Look for:

  • Encapsulated formulations
  • Airless pump packaging
  • Combination with Vitamin E (stabilizes resveratrol)
  • Green Tea (EGCG)

    Epigallocatechin gallate (EGCG) is green tea's most potent polyphenol:

  • 200x more antioxidant power than Vitamin E
  • Reduces UV-induced DNA damage
  • Anti-inflammatory for conditions like rosacea
  • May help with acne by reducing sebum
  • Ferulic Acid

    A key supporting player:

  • Stabilizes Vitamin C and E in formulations
  • Provides its own UV-absorbing properties
  • Enhances overall antioxidant efficacy by 2x
  • How to Use Polyphenols

  • Apply in the morning for daytime antioxidant protection
  • Layer under sunscreen - they complement UV filters
  • Look for stable formulations - dark bottles, airless pumps
  • Combine with Vitamin C and E for synergistic benefits
  • The Bottom Line

    Polyphenols are valuable additions to any anti-aging routine. While they may not replace retinoids, they provide essential antioxidant support that protects your skin from environmental damage.

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    Tags

    resveratrolpolyphenolsgreen teaferulic acidantioxidantanti-aging

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